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[B-pseudolymphoma: lymphocytoma].

A Torres Cortijo, A Ortíz Medina

    Medicina Cutanea Ibero-Latino-Americana
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Pseudolymphoma, including lymphocytoma cutis, presents diagnostic challenges differentiating it from malignant lymphoma. Long-term monitoring is crucial, especially for the multiple-lesion form, due to potential malignant transformation.

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    Area of Science:

    • Dermatology
    • Pathology
    • Oncology

    Background:

    • Pseudolymphoma concepts, classifications, and differentiation from malignant lymphoma require revision.
    • Lymphocytoma cutis, a form of pseudolymphoma, presents diagnostic challenges due to overlapping clinical and histological features with malignant lymphoma.

    Observation:

    • Ten cases of lymphocytoma cutis are presented as a paradigm of B pseudolymphoma, highlighting clinical and histological controversies.
    • Lesions are typically papulo-tuberous with an "orange skin" appearance, often on the head, and can mimic malignant lymphoma.
    • Histology shows dense, polymorphous lymphocytic proliferation in diffuse or nodular patterns, characteristic of B pseudolymphoma.

    Findings:

    • Lymphocytoma cutis encompasses various entities like Spiegler-Fendt Sarcoid and Jessner's lymphocytic infiltration.

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  • Two clinical forms are identified: single-nodular and multiple-diffuse, with distinct characteristics and potential for malignant transformation.
  • One case evolved into malignant lymphoma after 30 years, emphasizing the need for vigilance.

    • Implications:

    • Clearer diagnostic criteria are needed to distinguish pseudolymphoma from malignant lymphoma.
    • The multiple-lesion form of lymphocytoma cutis warrants heightened awareness due to associated adenopathies and malignant potential.
    • Lifetime monitoring is strongly recommended for patients diagnosed with lymphocytoma cutis, particularly the multiple-lesion variant.