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HENLE FIBER LAYER MAPPING WITH DIRECTIONAL OPTICAL COHERENCE TOMOGRAPHY.

Cem Kesim1, Sevval Nur Bektas2, Zeynep Kulali2

  • 1Department of Ophthalmology, Koç University School of Medicine, Istanbul, Turkey.

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Summary

This study mapped the Henle fiber layer (HFL) in healthy eyes, providing normative data for HFL volume and thickness. This structural analysis is crucial for understanding HFL in various eye diseases.

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Area of Science:

  • Ophthalmology
  • Retinal Imaging
  • Optical Coherence Tomography

Background:

  • The Henle fiber layer (HFL) is a critical component of the retina, yet its detailed morphology is not fully characterized.
  • Understanding HFL structure is essential for diagnosing and monitoring retinal diseases.

Purpose of the Study:

  • To conduct a macular volumetric and topographic analysis of the Henle fiber layer (HFL).
  • To establish normative data for HFL morphology using optical coherence tomography (OCT).

Main Methods:

  • Retinal scans of 30 healthy eyes were acquired using spectral-domain OCT.
  • Manual segmentation of the HFL was performed on tilted OCT images.
  • Total HFL volume, mean thickness, and coverage area were calculated.

Main Results:

  • The mean total HFL volume was 0.74 ± 0.08 mm³.
  • Mean HFL thickness was 26.5 ± 2.9 µm, with the thickest measurements in the central macula.
  • HFL mapping revealed significant variations across macular quadrants.

Conclusions:

  • Henle fiber layer mapping is a valuable tool for structural analysis.
  • Establishing normative HFL morphology data is vital for future research into ocular and systemic disorders affecting the HFL.