Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

334
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
334
Human Genetics01:28

Human Genetics

754
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
754
Epigenetic Regulation01:46

Epigenetic Regulation

31.4K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
31.4K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

570
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
570
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

35.4K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.4K
Gene-Environment Interactions01:20

Gene-Environment Interactions

611
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
611

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between DNA methylation at birth and cognitive outcomes from early childhood to adolescence: A systematic review.

Neuroscience and biobehavioral reviews·2025
Same author

Feasibility of self-administered dried blood spot collection for cardiometabolic profile analysis in a population-based sample of young adults.

PloS one·2025
Same author

Consortium profile: the methylation, imaging and NeuroDevelopment (MIND) consortium.

Molecular psychiatry·2025
Same author

Effect of ultra-processed food consumption on male reproductive and metabolic health.

Cell metabolism·2025
Same author

Report of the 19th International Congress on Twin Studies, 26-28 September 2024, Assisi, Italy.

Twin research and human genetics : the official journal of the International Society for Twin Studies·2025
Same author

Epigenetic age across development in children and adolescents with ADHD.

Psychiatry research·2025

Related Experiment Video

Updated: Sep 24, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

15.9K

Epigenetics and ADHD.

Timothy Silk1,2, Lillian Dipnall3, Yen Ting Wong4

  • 1Centre for Social and Early Emotional Development and School of Psychology, Deakin University, Geelong, VIC, Australia. tim.silk@deakin.edu.au.

Current Topics in Behavioral Neurosciences
|May 3, 2022
PubMed
Summary
This summary is machine-generated.

Epigenetics may explain some Attention-Deficit Hyperactivity Disorder (ADHD) variability not due to genetics. Further research into epigenetic processes could reveal predictive and protective links for ADHD.

Keywords:
Candidate geneEWASEpigeneticEpigenomeMethylation

More Related Videos

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
13:09

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

10.4K
Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
05:44

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

736

Related Experiment Videos

Last Updated: Sep 24, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

15.9K
Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol
13:09

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

10.4K
Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
05:44

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

736

Area of Science:

  • Neuroscience
  • Genetics
  • Developmental Psychology

Background:

  • Genetic factors contribute to Attention-Deficit Hyperactivity Disorder (ADHD) susceptibility.
  • Significant variability in ADHD remains unexplained by genetics alone.
  • Epigenetics offers a potential mechanism for understanding this variability.

Purpose of the Study:

  • To review the current state of epigenetic research in ADHD.
  • To discuss key epigenetic processes relevant to ADHD.
  • To summarize findings from human epigenetic studies on ADHD.

Main Methods:

  • Review of epigenetic processes (e.g., DNA methylation, histone modification).
  • Analysis of human studies including candidate-gene studies (CGS).
  • Exploration of epigenome-wide association studies (EWAS) in ADHD.

Main Results:

  • Epigenetic modifications influence neurobiological and developmental pathways.
  • Current epigenetic findings in ADHD are heterogeneous.
  • Disturbances in epigenetic processes may impact mental health.

Conclusions:

  • Epigenetics is a promising area for ADHD research.
  • Longitudinal studies and well-characterized cohorts are needed.
  • Future research may uncover predictive and protective epigenetic links to ADHD.