Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

114
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
114
Connective Tissue Cell Types01:22

Connective Tissue Cell Types

3.5K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.5K
Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

3.1K
Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
3.1K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

65
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
65
Introduction to Connective Tissues01:11

Introduction to Connective Tissues

10.9K
Connective tissues are one of the four main tissue types in humans that are extensively present in the body. They are characterized by cells embedded in an extracellular matrix (ECM) composed of a ground substance and three main types of protein fibers— collagen, elastic, and reticular fibers. The ground substance of connective tissues can range from a watery and jelly-like consistency to mineralized and hard. The wide variety of cells in the connective tissues include fibroblasts,...
10.9K
Hypertension I: Introduction01:28

Hypertension I: Introduction

104
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
104

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular analysis in 12 factor XI deficiency patients from China: Identification of three novel splicing mutations.

Thrombosis research·2020
Same author

Genome-wide study of saprotrophy-related genes in the basal fungus Conidiobolus heterosporus.

Applied microbiology and biotechnology·2020
Same author

Association of circulating CEACAM1 levels and insulin sensitivity in gestational diabetes mellitus.

BMC endocrine disorders·2020
Same author

Refining the Life Cycle of <i>Plasmodiophora brassicae</i>.

Phytopathology·2020
Same author

The Relation between Volume and Outcome of Transcatheter and Surgical Aortic Valve Replacement: A Systematic Review and Meta-Analysis.

Cardiovascular therapeutics·2020
Same author

Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.

Journal of Cancer·2020

Related Experiment Video

Updated: Sep 24, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.4K

Hypertension in connective tissue disease.

Qiang Luo1, Yiwen Zhang1, Xiaoqian Yang1

  • 1Department of Cardiology, Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, 82 Qinglong St., Chengdu, Sichuan, China.

Journal of Human Hypertension
|May 3, 2022
PubMed
Summary

Connective tissue disease (CTD) patients have higher hypertension rates. This review examines CTD-hypertension links, focusing on risk factors and management strategies for cardiovascular disease prevention.

More Related Videos

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

858
Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension
09:20

Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension

Published on: January 28, 2017

18.4K

Related Experiment Videos

Last Updated: Sep 24, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.4K
Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug
05:57

Author Spotlight: Exploring Huotan Jiedu Tongluo Decoction as an Antihypertensive Drug

Published on: May 17, 2024

858
Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension
09:20

Intracellular Staining and Flow Cytometry to Identify Lymphocyte Subsets within Murine Aorta, Kidney and Lymph Nodes in a Model of Hypertension

Published on: January 28, 2017

18.4K

Area of Science:

  • Rheumatology
  • Cardiology
  • Internal Medicine

Background:

  • Connective tissue disease (CTD) is an autoimmune disorder causing chronic inflammation across organ systems.
  • Patients with CTD exhibit a higher prevalence of hypertension (HT) compared to the general population.
  • Cardiovascular disease (CVD) risk is elevated in CTD patients, with HT being a significant contributing factor.

Purpose of the Study:

  • To explore the pathogenesis of hypertension in CTD patients.
  • To identify factors contributing to elevated blood pressure (BP) in CTD.
  • To review the management of CTD-associated HT and its relationship with traditional cardiovascular risk factors.

Main Methods:

  • Literature review focusing on CTD, hypertension, and cardiovascular disease.
  • Analysis of existing data on the prevalence and risk factors of HT in CTD.
  • Examination of potential mechanisms linking CTD, HT, and cardiovascular outcomes.

Main Results:

  • CTD is associated with an increased risk of HT, partly due to traditional cardiovascular risk factors.
  • The precise mechanisms underlying CTD-associated HT require further investigation.
  • Controlling BP is crucial for CVD prevention in CTD patients.

Conclusions:

  • Understanding the pathogenesis of HT in CTD is essential for effective CVD risk management.
  • Further research is needed to confirm the role of traditional risk factors, disease activity, and medications in CTD-HT.
  • Integrated management strategies are necessary to address both CTD and HT in affected individuals.