[Aortic coarctation and osteogenesis imperfecta]

This is the report of a 4 year old patient with osteogenesis imperfecta tarda and aortic coarctation. The resection of the aortic coarctation was performed when the patient was 5 years old. Postoperative recovery and formation of scar tissue presented no problems. Increased operation risk due to osteogenesis imperfecta (White et al., 1983) and possible abnormal formation of scar tissue due to this collagen disorder necessitated detailed preoperative tests of collagen metabolism. We shall discuss the histological and biochemical results of these tests and evaluate the effect of therapy with catechin.