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Updated: Sep 24, 2025

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Endoscopic Mucosal Resection: Best Practices for Gastrointestinal Endoscopists
Sushrut Sujan Thiruvengadam1, Brian M Fung2, Monique T Barakat3
1Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, California.
Endoscopic mucosal resection (EMR) effectively removes large colorectal polyps. Careful patient selection and surveillance are crucial to manage risks like bleeding and recurrence after EMR procedures.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic mucosal resection (EMR) is a key technique for gastrointestinal lesion removal.
- Large colorectal polyps are the primary indication for EMR, necessitating specialized evaluation.
Purpose of the Study:
- To review endoscopic mucosal resection (EMR) techniques for large colorectal polyps.
- To discuss polyp evaluation, EMR methods, adverse events, and post-procedure surveillance.
Main Methods:
- Review of conventional hot-snare EMR with submucosal injection.
- Exploration of alternative EMR techniques: cold-snare and underwater EMR.
- Discussion of polyp evaluation methods for EMR feasibility.
Main Results:
- EMR is feasible for sessile or flat gastrointestinal lesions, particularly large colorectal polyps.
- Key adverse events include bleeding, perforation, and post-polypectomy coagulation syndrome.
- Surveillance is essential due to the possibility of residual or recurrent polyps.
Conclusions:
- EMR is a valuable endoscopic technique for large colorectal polyps.
- Appropriate patient selection and post-EMR surveillance are critical for optimal outcomes.
- Understanding EMR techniques and risks minimizes complications and ensures effective polyp management.
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