A method for studying reinforcement factors controlling impulsive choice for use in behavioral neuroscience

Although procedures originating within the experimental analysis of behavior commonly are used in behavioral neuroscience to produce behavioral endpoints, they are used less often to analyze the behavioral processes involved, particularly at the level of individual organisms (see Soto, 2020). Concurrent-chains procedures have been used extensively to study choice and to quantify relations between various dimensions of reinforcement and preference. Unfortunately, parametric analysis of those relations using traditional steady-state, single-subject experimental designs can be time-consuming, often rendering these procedures impractical for use in behavioral neuroscience. The purpose of this paper is to describe how concurrent-chains procedures can be adapted to allow for parametric examination of effects of the reinforcement dimensions involved in impulsive choice (magnitude and delay) within experimental sessions in rats. Data are presented indicating that this procedure can produce relatively consistent within-session estimates of sensitivity to reinforcement in individual subjects, and that these estimates can be modified by neurobiological manipulation (drug administration). These data suggest that this type of procedure offers a promising approach to the study of neurobiological mechanisms of complex behavior in individual organisms, which could facilitate a more fruitful relationship between behavior analysis and behavioral neuroscience.