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Clinical and echocardiographic characteristics in patients with heart failure and type 2 diabetes

Mikel Jordhani1, Joana Seiti2, Vivencio Barrios3

  • 1Internal Medicine Department, Korça Regional Hospital, Korçë, 7001, Albania.

Future Cardiology
|May 4, 2022
PubMed

Insights

Type 2 diabetes (T2D) is linked to more severe heart failure (HF) and cardiac changes. Poor diabetes control worsens cardiovascular outcomes in HF patients.

Area of Science:

  • Cardiology
  • Endocrinology
  • Internal Medicine

Background:

  • Type 2 diabetes (T2D) and heart failure (HF) frequently coexist, complicating cardiovascular diagnosis and management.
  • Understanding the interplay between T2D and HF is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the association between T2D and the clinical and echocardiographic features of patients diagnosed with HF.
  • To investigate how T2D impacts cardiac structure and function in HF patients.

Main Methods:

  • A case-control study involving 121 patients with HF.
  • Patients were categorized into two groups: those with T2D and those without.
  • Echocardiographic assessments were performed, and patients with T2D were further analyzed based on HbA1c control.

Main Results:

  • Significant differences were observed between T2D and non-T2D groups in left atrial diameter, E/E' ratio, and left ventricular end-diastolic diameter.
  • Among patients with T2D, poor glycemic control (indicated by HbA1c) correlated with increased acute HF episodes, reduced left ventricular ejection fraction, and altered left atrial diameter and E/E' ratio.

Conclusions:

  • T2D is associated with significant cardiac alterations and contributes to more severe heart failure.
  • Suboptimal diabetes management in HF patients leads to poorer cardiovascular outcomes.

Keywords:
diabetic cardiomyopathydiastolic dysfunctionechocardiographyglycated hemoglobinheart failuretype 2 diabetes

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