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Updated: Sep 24, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
[Newborn with syphilitic pemphigus in pandemic's time]
Claudia Aguilante1, José Andrés Durán1, Eduardo Ahumada2
1Escuela de Medicina, Universidad de Valparaíso, Chile.
Insights
Congenital syphilis, a preventable infection, poses risks to newborns if mothers aren't treated. This case highlights the importance of prenatal care and screening for Treponema pallidum.
Area of Science:
- Neonatology
- Infectious Diseases
- Public Health
Background:
- Congenital syphilis results from mother-to-child transmission of Treponema pallidum during pregnancy.
- It is a significant cause of preventable fetal and neonatal morbidity and mortality.
- Adequate prenatal care, early screening, and timely treatment are crucial for prevention.
Observation:
- Chile maintains a stable congenital syphilis rate despite rising general syphilis incidence.
- This case report details a newborn whose mother lacked antenatal care.
- The mother presented with dermatological lesions suggestive of syphilitic pemphigus.
Findings:
- The case underscores the persistent risk of congenital syphilis, particularly in pregnancies without prenatal surveillance.
- Syphilitic pemphigus in the newborn can be a clinical sign of congenital infection.
- Early detection and intervention are critical for preventing severe outcomes.
Implications:
- Reinforces the need for robust prenatal screening programs to detect and treat maternal syphilis.
- Highlights the importance of recognizing clinical signs of congenital syphilis in newborns.
- Emphasizes the ongoing public health challenge of congenital syphilis transmission.
Abstract:
Congenital syphilis is the infection by Treponema pallidum of the newborn, due to mother-to-child transmission of spirochaetes during pregnancy. It remains as a major cause of preventable fetal and neonatal morbidity and mortality if the mother is not opportunely treated. This highlights the importance of an adequate prenatal control, early screening for maternal infection and timely treatment. Although Chile has experienced an increase in the incidence of syphilis in the general population, a stable rate of congenital syphilis in 0.1/1.000 live births has been maintained. In this case report, we present a newborn whose mother did not have antenatal control and showed dermatological lesions compatible with syphilitic pemphigus.
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