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Updated: Sep 24, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Palladium-Catalyzed Aminocarbonylation of Aryl Halides
Cheriya Mukkolakkal Abdulla Afsina1, Rose Mary Philip1, Padinjare Veetil Saranya1
1School of Chemical Sciences, Mahatma Gandhi University, Priyadarsini Hills P. O, Kottayam, Kerala 686560, India.
Abstract:
Palladium-catalyzed organic reactions are ubiquitous due to their high efficiency in coupling reactions and have wide applications in synthetic chemistry. Their widespread use in organic synthesis has been attributed to moderate conditions associated with reactions and tolerance to different types of functional groups. Palladium-catalysts are extensively used in aminocarbonylation of aryl halides for the synthesis of amides and have found a wide variety of applications in pharmaceuticals, agrochemicals, petrochemicals, materials, polymers, etc. In this review, we summarize the recent advances in the synthesis of amides via palladium-catalyzed aminocarbonylation of aryl halides, and cover literature from 2010 to 2021.
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