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Esophageal Perforation-I: Introduction01:22

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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Related Experiment Video

Updated: Sep 24, 2025

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
09:24

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

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Small intestinal press-through package perforation.

Toshimasa Yamaguchi1

  • 1Primary Care and Advanced Triage Section Osaka City General Hospital Osaka Japan.

Journal of General and Family Medicine
|May 5, 2022
PubMed
Summary
This summary is machine-generated.

A 75-year-old man experienced severe abdominal pain due to a swallowed tablet in its packaging. Imaging confirmed a press-through package tablet lodged in the terminal ileum, causing peritonitis.

Keywords:
foreign body ingestionimagingintestinal perforationperitonitispress‐through packagesmall intestine

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Area of Science:

  • Gastroenterology
  • Radiology
  • Abdominal Imaging

Background:

  • Abdominal pain is a common presenting complaint in emergency departments.
  • Terminal ileum pathology can present with non-specific symptoms.
  • Foreign body ingestion requires prompt diagnosis and management.

Observation:

  • A 75-year-old male presented with acute worsening abdominal pain.
  • Contrast-enhanced computed tomography (CECT) demonstrated terminal ileum wall thickening and peritonitis.
  • A distinct CECT finding of a round, high-density object with a surrounding low-density halo was identified within the terminal ileum.

Findings:

  • The imaging characteristics were pathognomonic for a tablet within a press-through package (PTP).
  • The PTP tablet was located in the terminal ileum, causing significant inflammation and localized peritonitis.
  • This case highlights a rare cause of acute abdominal pathology secondary to foreign body ingestion.

Implications:

  • Press-through package tablets can cause serious gastrointestinal complications, including obstruction and perforation.
  • Radiologists and clinicians should be aware of the characteristic CECT findings of PTP tablets.
  • Early recognition and surgical intervention are crucial for managing PTP tablet-induced complications.