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Related Concept Videos

Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

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The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form...
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Related Experiment Video

Updated: Sep 24, 2025

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
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Spinal deformity correction in ankylosing spondylitis.

Dominic Maggio1, Andrew Grossbach1, David Gibbs2

  • 1Department of Neurological Surgery, The Ohio State University Wexner Medical Center.

Surgical Neurology International
|May 5, 2022
PubMed
Summary

Ankylosing spondylitis (AS) surgery can improve pain, disability, and organ function, but requires careful consideration of risks like vertebral body osteotomy for deformity correction.

Keywords:
Ankylosing spondylitisDeformityOsteotomySpondyarthropathy

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Area of Science:

  • Orthopedics
  • Rheumatology
  • Surgical Science

Background:

  • Ankylosing spondylitis (AS) is a complex and debilitating spinal disease.
  • Limited effective medical therapies exist for advanced stages of AS.

Purpose of the Study:

  • To review current clinical management of AS patients.
  • To emphasize surgical intervention risks and outcomes.

Main Methods:

  • Literature review of clinical approaches for AS.
  • Focus on surgical interventions and their associated risks and benefits.

Main Results:

  • Vertebral body osteotomy may be necessary for spinopelvic realignment in AS surgery.
  • Surgical intervention can lead to significant improvements in pain, disability, cardiac function, respiration, digestion, and sexual activity.

Conclusions:

  • Deformity correction in AS patients requires careful consideration.
  • Surgical outcomes for AS patients should be weighed against potential risks.