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Successful management of testicular primitive neuroectodermal tumor with multiple bone metastases
Takuya Takasawa1, Tomonori Minagawa1, Takahisa Domen1
1Department of Urology Shinshu University School of Medicine Matsumoto Japan.
Introduction:
Germ cell tumor with malignant transformation is extremely rare. We present a case of testicular primitive neuroectodermal tumor with multiple metastases that was effectively managed by surgery, irradiation, and second-line chemotherapy.
Case Presentation:
A 22-year-old man was diagnosed as having teratoma including primitive neuroectodermal tumor with lymph node and multiple bone metastases. Five months afterwards the first-line therapy, his skull metastasis recurred. Vincristine, doxorubicin, and cyclophosphamide therapy followed by vincristine, actinomycin D, and cyclophosphamide therapy was given as second-line chemotherapy. Computed tomography revealed no disease progression 3 months after the treatments.
Conclusion:
Metastatic primitive neuroectodermal tumor may be successfully managed by multidisciplinary cancer treatment.
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