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Updated: Sep 24, 2025

Fabrication of Micro-Patterned Chip with Controlled Thickness for High-Throughput Cryogenic Electron Microscopy
Published on: April 21, 2022
Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples
Keisuke Oshimi1,2, Yushi Nishimura2,3, Tsutomu Matsubara4
1Department of Chemistry, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan. masazumi@okayama-u.ac.jp.
Abstract:
We report a notch-shaped coplanar microwave waveguide antenna on a glass plate designed for on-chip detection of optically detected magnetic resonance (ODMR) of fluorescent nanodiamonds (NDs). A lithographically patterned thin wire at the center of the notch area in the coplanar waveguide realizes a millimeter-scale ODMR detection area (1.5 × 2.0 mm2) and gigahertz-broadband characteristics with low reflection (∼8%). The ODMR signal intensity in the detection area is quantitatively predictable by numerical simulation. Using this chip device, we demonstrate a uniform ODMR signal intensity over the detection area for cells, tissue, and worms. The present demonstration of a chip-based microwave architecture will enable scalable chip integration of ODMR-based quantum sensing technology into various bioassay platforms.

