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Glass-patternable notch-shaped microwave architecture for on-chip spin detection in biological samples.

Keisuke Oshimi1,2, Yushi Nishimura2,3, Tsutomu Matsubara4

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Summary

We developed a chip-based antenna for detecting optically detected magnetic resonance (ODMR) in nanodiamonds. This innovation enables scalable quantum sensing for various bioassays.

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Area of Science:

  • Quantum Sensing
  • Microwave Engineering
  • Nanotechnology

Background:

  • Optically Detected Magnetic Resonance (ODMR) is a powerful technique for probing spin properties.
  • Current ODMR setups often lack scalability and on-chip integration for biological applications.

Purpose of the Study:

  • To design and demonstrate a chip-based microwave antenna for on-chip ODMR detection.
  • To enable scalable integration of ODMR quantum sensing into bioassay platforms.

Main Methods:

  • Fabrication of a notch-shaped coplanar waveguide antenna on a glass substrate using lithography.
  • Characterization of the antenna's detection area, broadband characteristics, and reflection.
  • Demonstration of uniform ODMR signal detection across various biological samples.

Main Results:

  • A millimeter-scale (1.5 × 2.0 mm²) ODMR detection area with gigahertz-broadband characteristics and low reflection (<8%).
  • Quantitative predictability of ODMR signal intensity via numerical simulation.
  • Uniform ODMR signal detection demonstrated for cells, tissue, and worms.

Conclusions:

  • The chip-based microwave antenna facilitates on-chip ODMR detection of fluorescent nanodiamonds.
  • This architecture enables scalable integration of ODMR quantum sensing into diverse bioassay platforms.