Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Association Areas of the Cortex01:21

Association Areas of the Cortex

6.4K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.4K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

1.1K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Enhanced disgust generalization in obsessive-compulsive disorder is related to insula and putamen hyperactivity - CORRIGENDUM.

Psychological medicine·2026
Same author

Angiotensin II regulates anxiety and social-affective top-down and bottom-up attention control in a sex-dependent manner.

Journal of affective disorders·2026
Same author

Chronic pain and stress: Transdiagnostic meta-analytic evidence of convergent network signature with PTSD.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same author

Modulation of emotion regulation deficits in patients with heroin use disorder by intermittent Theta-burst transcranial magnetic stimulation.

Progress in neuro-psychopharmacology & biological psychiatry·2026
Same author

Top-down rather than bottom-up attention processing mediates the pathway from childhood trauma exposure to depression in adolescents.

Journal of psychiatric research·2026
Same author

How Standardized Is Transcranial Magnetic Stimulation Treatment for Depression? Large-Cohort Modeling Reveals Systematic Dosimetric Variability.

Psychotherapy and psychosomatics·2026

Related Experiment Video

Updated: Sep 24, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.4K

Structural-functional connectivity mapping of the insular cortex: a combined data-driven and meta-analytic topic

Benjamin Klugah-Brown1, Pan Wang1, Yuan Jiang1

  • 1MOE Key Laboratory for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, Center for Information in Medicine, School of Life Science and Technology, University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave, West Hi-Tech Zone, 611731 Chengdu, China.

Cerebral Cortex (New York, N.Y. : 1991)
|May 5, 2022
PubMed
Summary

This study reveals strong links between structural and functional brain connectivity in the insular cortex. These findings offer new insights for understanding neurological disorders involving the insula.

Keywords:
DTIHuman Connectome Projectinsularresting-state functional connectivity

More Related Videos

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.7K
Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

12.4K

Related Experiment Videos

Last Updated: Sep 24, 2025

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.4K
Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.7K
Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

12.4K

Area of Science:

  • Neuroscience
  • Brain Imaging
  • Connectomics

Background:

  • The insular cortex plays a crucial role in integrating cognitive, affective, and sensory information.
  • Understanding the structural and functional organization of the insula is vital for comprehending brain function and dysfunction.

Approach:

  • Utilized diffusion tensor imaging (DTI) and resting-state functional connectivity (RSFC) data from the Human Connectome Project (108 adults).
  • Employed a data-driven method to independently estimate structural-functional connectivity of insular subregions.
  • Integrated meta-analytic decoding maps to explore cognitive, affective, and gene expression profiles.

Key Points:

  • Demonstrated moderate to high associations between structural and functional mapping scores for posterior, dorsal anterior, and ventral anterior insula subregions.
  • Posterior insula showed strong links to the sensorimotor network (RSFC 50%, DTI 72%).
  • Dorsal anterior insula strongly associated with ventral attention network (RSFC 83%, DTI 83%).
  • Ventral anterior insula linked to the frontoparietal network (RSFC 42%, DTI 89%).

Conclusions:

  • The study highlights significant correspondence between DTI and RSFC, providing a complementary approach to brain mapping.
  • Findings offer valuable insights for clinical researchers studying neurological disorders with insular pathology.
  • This research enhances our understanding of the insular cortex's role in brain organization and its implications for neurological conditions.