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Updated: Sep 24, 2025
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Ligament Advanced Reinforcement System (LARS) synthetic graft for PCL reconstruction: systematic review and
Filippo Migliorini1, Andrea Pintore2, Gianluca Vecchio2
1Department of Orthopaedics, University Clinic Aachen, RWTH Aachen University Clinic, 52064 Aachen, Germany.
Introduction:
Several strategies are available for posterior cruciate ligament (PCL) reconstruction.
Source Of Data:
Recently published literature in PubMed, Google Scholar and Embase databases.
Areas Of Agreement:
The Ligament Advanced Reinforcement System (LARS) is a scaffold type artificial ligament, which has been widely used for ligament reconstruction of the knee.
Areas Of Controversy:
Current evidence on the reliability and feasibility of LARS for primary isolated PCL reconstruction is limited.
Growing Points:
The primary outcome of interest of the present work was to investigate the outcomes of PCL reconstruction using the LARS. The secondary outcome of interest was to compare the LARS versus four-strand hamstring tendon (4SHT) autograft for PCL reconstruction.
Areas Timely For Developing Research:
LARS for primary isolated PCL reconstruction seems to be effective and safe, with results comparable to the 4SHT autograft.
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