Antibody induced elimination of the plasmid controlled K88 adhesion factor from a porcine enteropathogen

The heat labile K88 antigen which is a product of an episomal gene, was eliminated from a pocrine enteropathogen by passage through media containing sow colostrum antibodies raised against heart stable antigens of E. coli. In consequence the porcine enteropathogen lost its ability to adhere to and aggluinate chicken erythrocytes, and model system for piglet intestinal adhesion and virulence.