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Optical flexible biosensors: From detection principles to biomedical applications
Wanxia Wu1, Lan Wang1, Ya Yang1
1Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing, 211800, China.
Biosensors & Bioelectronics
|May 5, 2022
Summary
Optical flexible biosensors offer adaptable, real-time analyte detection for in vitro and in vivo health monitoring. This review covers their principles, applications, and future development for disease diagnosis and health detection.
Area of Science:
- Biomedical Engineering
- Materials Science
- Analytical Chemistry
Background:
- Optical flexible biosensors utilize adaptable materials for analyte detection.
- They offer advantages over traditional sensors, including enhanced flexibility for diverse applications.
- These sensors enable both in vitro analysis and real-time, non-invasive in vivo monitoring.
Purpose of the Study:
- To review the detection principles, key analytes, and applications of optical flexible biosensors.
- To highlight their role in disease diagnosis, treatment, and general health detection.
- To address current challenges and future perspectives in the field.
Main Methods:
- Review of existing literature on optical flexible biosensors.
- Analysis of detection mechanisms and materials.
- Compilation of applications in medical and health-related fields.
Main Results:
- Optical flexible biosensors demonstrate significant potential for various diagnostic and monitoring tasks.
- Their flexibility allows for integration into wearable devices and adaptation to biological environments.
- The review consolidates current knowledge on principles, analytes, and applications.
Conclusions:
- Optical flexible biosensors are a rapidly advancing technology with broad applications in healthcare.
- Further research is needed to overcome existing challenges and enhance device functionality.
- These biosensors promise more feasible and multifunctional solutions for disease diagnosis and health monitoring.

