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Factors affecting mechanical complications of central venous access devices in children
Jessica J Zhang1, Ramesh M Nataraja1,2,3, Amiria Lynch1
1Department of Paediatric Surgery, Monash Children's Hospital, 246 Clayton Road, Clayton, VIC, 3168, Australia.
Insights
Mechanical complications affect 17% of central venous access devices (CVADs) in children, with younger age and lower weight increasing risk. Implantable ports show fewer issues than Hickman lines.
Area of Science:
- Pediatric Surgery
- Medical Devices
- Vascular Access
Background:
- Mechanical complications of central venous access devices (CVADs) in pediatric patients are not well understood.
- Identifying risk factors and rates is crucial for improving patient outcomes.
Purpose of the Study:
- To quantify the incidence of mechanical complications in pediatric CVADs.
- To investigate the mechanisms and associated risk factors for these complications.
Main Methods:
- Retrospective review of 317 CVADs inserted in children under 18 between 2016-2021.
- Statistical analysis including Fisher's exact test, chi-squared test, and logistic regression.
- Data categorized by complication type, device type, patient age, and weight.
Main Results:
- Overall, 17% of CVADs experienced mechanical complications within a median of <6 months post-insertion.
- Fracture (6%), CVAD migration (4.4%), and occlusion (4.4%) were the most common complications.
- Younger age and lower weight were significant risk factors (p < 0.0001). Hickman lines had a higher complication rate (26.3%) than implantable ports (13.3%, p=0.008).
Conclusions:
- Mechanical complications are a significant concern in pediatric CVADs, occurring in 17% of cases.
- Risk is elevated in younger, lighter children.
- Implantable port devices demonstrate a lower incidence of mechanical complications compared to Hickman lines, suggesting they may be a safer option in certain pediatric populations.
Purpose:
Factors leading to mechanical complications following insertion of central venous access devices (CVADs) in children are poorly understood. We aimed to quantify the rates and elucidate the mechanisms of these complications.
Methods:
Retrospective (2016-2021) review of children (< 18 years old) receiving a CVAD. Data, reported as number of cases (%) and median (IQR), were analysed by Fisher's exact test, chi-squared test and logistic regression analysis.
Results:
In total, 317 CVADs (245 children) were inserted. Median age was 5.0 (8.9) years, with 116 (47%) females. There were 226 (71%) implantable port devices and 91 (29%) Hickman lines. Overall, 54 (17%) lines had a mechanical complication after 0.4 (0.83) years from insertion: fracture 19 (6%), CVAD migration 14 (4.4%), occlusion 14 (4.4%), port displacement 6 (1.9%), and skin tethering to port device 1 (0.3%). Younger age and lower weight were associated with higher risk of complications (p < 0.0001). Hickman lines had a higher incidence of complications compared to implantable port devices [24/91 (26.3%) vs 30/226 (13.3%); p = 0.008].
Conclusion:
Mechanical complications occur in 17% of CVADs at a median of < 6 months after insertion. Risk factors include younger age and lower weight. Implantable port devices have a lower complications rate.
Level Of Evidence:
Level 4: case-series with no comparison group.
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