Factors affecting mechanical complications of central venous access devices in children

Jessica J Zhang1, Ramesh M Nataraja1,2,3, Amiria Lynch1

  • 1Department of Paediatric Surgery, Monash Children's Hospital, 246 Clayton Road, Clayton, VIC, 3168, Australia.

Insights

Mechanical complications affect 17% of central venous access devices (CVADs) in children, with younger age and lower weight increasing risk. Implantable ports show fewer issues than Hickman lines.

Area of Science:

  • Pediatric Surgery
  • Medical Devices
  • Vascular Access

Background:

  • Mechanical complications of central venous access devices (CVADs) in pediatric patients are not well understood.
  • Identifying risk factors and rates is crucial for improving patient outcomes.

Purpose of the Study:

  • To quantify the incidence of mechanical complications in pediatric CVADs.
  • To investigate the mechanisms and associated risk factors for these complications.

Main Methods:

  • Retrospective review of 317 CVADs inserted in children under 18 between 2016-2021.
  • Statistical analysis including Fisher's exact test, chi-squared test, and logistic regression.
  • Data categorized by complication type, device type, patient age, and weight.

Main Results:

  • Overall, 17% of CVADs experienced mechanical complications within a median of <6 months post-insertion.
  • Fracture (6%), CVAD migration (4.4%), and occlusion (4.4%) were the most common complications.
  • Younger age and lower weight were significant risk factors (p < 0.0001). Hickman lines had a higher complication rate (26.3%) than implantable ports (13.3%, p=0.008).

Conclusions:

  • Mechanical complications are a significant concern in pediatric CVADs, occurring in 17% of cases.
  • Risk is elevated in younger, lighter children.
  • Implantable port devices demonstrate a lower incidence of mechanical complications compared to Hickman lines, suggesting they may be a safer option in certain pediatric populations.
Abstract

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