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Cerium oxide nanoparticles: properties, biosynthesis and biomedical application.

Kshitij Rb Singh1, Vanya Nayak1, Tanushri Sarkar1

  • 1Department of Biotechnology, Faculty of Science, Indira Gandhi National Tribal University Amarkantak Madhya Pradesh 484887 India rpsnpl69@gmail.com ravindra.singh@igntu.ac.in +91-91-0934-6565.

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Biosynthesis of cerium oxide nanoparticles offers a less toxic, biocompatible alternative for various applications. This review comprehensively covers their properties, biomedical uses, and future potential.

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Biomedical Engineering

Background:

  • Nanoparticles exhibit unique properties distinct from bulk materials.
  • Cerium oxide nanoparticles (nanoceria) show promise due to redox activity and free radical scavenging.
  • Biosynthesis offers a less toxic and more biocompatible route for nanoparticle production.

Purpose of the Study:

  • To provide a comprehensive review of cerium oxide nanoparticles, focusing on biosynthesis.
  • To explore the effects of biosynthesis on nanoceria's interaction with living tissues.
  • To detail the properties, biomedical applications, and future outlook of nanoceria.

Main Methods:

  • Focus on biosynthesis methods for cerium oxide nanoparticles.
  • Analysis of properties influenced by biosynthesis.
  • Review of existing literature on nanoceria's biomedical applications.

Main Results:

  • Biosynthesis yields less toxic and more biocompatible nanoceria.
  • Nanoceria demonstrate potential as anticancer, anti-inflammatory, and antibacterial agents.
  • Biosynthesis impacts nanoceria's properties and biological interactions.

Conclusions:

  • Biosynthesis is a key method for developing safe and effective cerium oxide nanoparticles.
  • Nanoceria hold significant potential for diagnostic and therapeutic biomedical applications.
  • Further research into biosynthesis and applications is warranted for future advancements.