Yttrium(iii) coordination polymer micro/nanospheres with single ligand and dual ligands

In this work, yttrium(iii) coordination polymer (Y-CP) ball-flower-shaped microparticles with diameters ranging from 5 μm to 10 μm were synthesized using vanillin and asparagine as ligands under solvothermal conditions at 150 °C for 24 h. Then, we investigated the reaction influencing factors such as the concentration of reactants (involving vanillin, asparagine, and rare earth), reaction temperature, and reaction time. Both uniform and sphere-like nanoparticles with an average size of ∼50 nm were obtained using vanillin as a ligand at 120 °C for 12 h. Furthermore, the products were characterized and the results of cytotoxicity research demonstrated that the nanoparticles had low cytotoxicity and the coordination polymer nanospheres were perfectly biocompatible.