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Vaccinations

Vaccinations

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Related Experiment Video

Updated: Sep 24, 2025

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

Post immunization COVID-19 disease.

Himmatrao S Bawaskar¹, Pramodini H Bawaskar¹

¹Department of Medicine, Bawaskar Hospital and Clinical Research Centre, Mahad, Raigad, Maharashtra, India.

Journal of Family Medicine and Primary Care

|May 6, 2022

Summary

This summary is machine-generated.

COVID-19 vaccination with Covishield and Covaxin showed varying effectiveness. A booster dose is recommended for all individuals experiencing COVID-19 symptoms, regardless of prior immunization status.

Keywords:

COVID-19 HRCT vaccine

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Area of Science:

Immunology
Infectious Diseases
Public Health

Background:

COVID-19 vaccination is crucial for public health.
Covishield and Covaxin are two primary vaccines used.
Understanding vaccine effectiveness in real-world settings is essential.

Observation:

A study included 102 patients with COVID-19, vaccinated with either Covishield or Covaxin.
Inflammatory markers were assessed in relation to vaccine type and disease severity.
Three deaths were reported among the vaccinated patients.

Findings:

Elevated inflammatory markers like C-reactive protein and serum ferritin were observed in both vaccine groups.
A significant percentage of vaccinated individuals tested positive for SARS-CoV-2 antigens and via RTPCR, indicating breakthrough infections.
COVID-19 pneumonia was diagnosed in a notable proportion of patients across both vaccination arms.

Implications:

The study highlights the need for continued monitoring of vaccine effectiveness against SARS-CoV-2.
Findings suggest that even vaccinated individuals with symptoms require thorough investigation for COVID-19.
The results strongly support the recommendation for a booster dose of COVID-19 vaccination to enhance protection.