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Updated: Sep 24, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
New anionic rhodium complexes as catalysts for the reduction of acetophenone and its derivatives
Olga Bartlewicz1, Magdalena Jankowska-Wajda1, Hieronim Maciejewski1,2
1Faculty of Chemistry, Adam Mickiewicz University in Poznań Umultowska 89B 61-614 Poznań Poland maciejm@amu.edu.pl.
Abstract:
New anionic rhodium(iii) complexes, obtained by a simple reaction of RhCl3 with organic chlorides (derivatives of imidazole and pyridine), have been employed as catalysts for hydrosilylation (reduction) of acetophenone derivatives. The reactions, in which 1,1,1,3,5,5,5-heptamethyltrisiloxane was a reducing agent, proceeded in a biphasic system because the above complexes are insoluble in the reaction medium. Thereby easy isolation of the complexes from post-reaction mixtures was possible after reaction completion. This is the first example of the application of rhodium complexes of this type as catalysts for ketone reduction. The complexes have shown high activity and enabled obtaining the hydrosilylation product in a very short time and in the range of low concentrations (0.1 mol%). By using FT-IR in situ analysis that enables measuring product concentrations in real time, a comparison has been made of the catalytic activity for hydrosilylation of acetophenone and methoxyacetophenone isomers shown by four rhodium complexes ([C+][RhCl4 -]) differing in cations and the most effective catalyst for this process has been distinguished.
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