Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Thyroid hormones and brain development.

J H Dussault, J Ruel

    Annual Review of Physiology
    |January 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Thyroid hormones are crucial for central nervous system development during a critical period. Understanding their mechanism of action, particularly the T3 receptor, is key to further research on brain maturation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Transient marked reactive lymphocytosis in a puppy suspected to be secondary to recent vaccination.

    The Journal of small animal practice·2026
    Same author

    Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

    The American journal of gastroenterology·2015
    Same author

    Dusty starburst galaxies in the early Universe as revealed by gravitational lensing.

    Nature·2013
    Same author

    Severe anaphylaxis caused by orally administered vancomycin to a patient with Clostridium difficile infection.

    Infection·2012
    Same author

    A massive, cooling-flow-induced starburst in the core of a luminous cluster of galaxies.

    Nature·2012
    Same author

    Comparison of three spike detectors dedicated to single unit action potentials of the auditory nerve.

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2007
    Same journal

    CaMKII in the Heart: From Homeostasis to Pathology.

    Annual review of physiology·2026
    Same journal

    Cerebrospinal Fluid-Mediated Brain Clearance: Insights from Human Studies.

    Annual review of physiology·2026
    Same journal

    The Physiological Challenge of Climate Change for Free-Living Terrestrial Mammals.

    Annual review of physiology·2026
    Same journal

    Light Out of Sight: Signaling Mechanisms for Nonvisual Opsins.

    Annual review of physiology·2025
    Same journal

    From Oil Spills to Air Pollution: The Emergence of Phenanthrene as a Ubiquitous Cardiac Toxicant.

    Annual review of physiology·2025
    Same journal

    The Representation of Nociception and Pain in the Developing Brain.

    Annual review of physiology·2025
    See all related articles

    Area of Science:

    • Neuroscience
    • Endocrinology
    • Developmental Biology

    Background:

    • Thyroid hormones play a vital role in central nervous system (CNS) maturation.
    • Absence of thyroid hormones during development has deleterious effects on the CNS.
    • A critical developmental window exists where thyroid hormones are essential for normal CNS maturation.

    Purpose of the Study:

    • To review the essential role of thyroid hormones in CNS development.
    • To explore the progress in understanding the molecular mechanisms of thyroid hormone action.
    • To highlight the importance of the nuclear T3 receptor in brain development.

    Main Methods:

    • Literature review focusing on the effects of thyroid hormone deficiency on CNS development.
    • Analysis of studies on the ontogenesis and distribution of the nuclear T3 receptor.

    Related Experiment Videos

  • Synthesis of anatomical, biochemical, and neurophysiological evidence.

    • Main Results:

    • Thyroid hormones are indispensable for normal CNS maturation during a specific critical period.
    • Studies on the nuclear T3 receptor have advanced understanding of thyroid hormone action.
    • The distribution and ontogenesis of the T3 receptor provide insights into molecular events controlling brain growth.

    Conclusions:

    • Thyroid hormones are critical for brain development, with absence causing significant deficits.
    • Further research into the T3 receptor and its role is needed to fully elucidate thyroid hormone-brain development relationships.