Related Experiment Video
Updated: Sep 24, 2025

A Cell Culture Model for Studying the Role of Neuron-Glia Interactions in Ischemia
Published on: November 14, 2020
Microglia: The Hub of Intercellular Communication in Ischemic Stroke
Yunsha Zhang1, Lu Lian2,3,4, Rong Fu2,3,4
1School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine Tianjin, China.
Abstract:
Communication between microglia and other cells has recently been at the forefront of research in central nervous system (CNS) disease. In this review, we provide an overview of the neuroinflammation mediated by microglia, highlight recent studies of crosstalk between microglia and CNS resident and infiltrating cells in the context of ischemic stroke (IS), and discuss how these interactions affect the course of IS. The in-depth exploration of microglia-intercellular communication will be beneficial for therapeutic tools development and clinical translation for stroke control.
Related Concept Videos
Glial Cells
Neurogenesis and Regeneration of Nervous Tissue

