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Updated: Sep 24, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
Published on: September 18, 2016
Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from
Xianheng Song1, Xiang Luo1, Jianfei Sheng1
1School of Pharmaceutical Sciences, Sun Yat-sen University Guangzhou 510640 P. R. China zou_jinan@163.com.
Abstract:
A copper-catalyzed intramolecular cross dehydrogenative C-O coupling reaction of 2'-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good functional group compatibility and was amenable to substrates with free phenolic hydroxyl groups.
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