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Updated: Sep 24, 2025

Synthesis of Esters Via a Greener Steglich Esterification in Acetonitrile
Published on: October 30, 2018
Cross-dehydrogenative coupling reactions between arenes (C-H) and carboxylic acids (O-H): a straightforward and
Sattar Arshadi1, Alireza Banaei1, Aazam Monfared1
1Department of Chemistry, Payame Noor University Tehran Iran.
Abstract:
Transition-metal catalyzed cross-dehydrogenative-coupling reactions encompass highly versatile and atom economical methods for the construction of various carbon-carbon and carbon-heteroatom bonds by combining two C(X)-H (X = heteroatom) bonds. Along this line, direct acyloxylation of C-H bonds with carboxylic acids has emerged as a powerful and green approach for the synthesis of structurally diverse esters. In this focus-review we will describe recent progress in direct esterification of aromatic C-H bonds with special emphasis on the mechanistic features of the reactions. Literature has been surveyed until the end of February 2019.
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