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Updated: Sep 24, 2025
Integration of Miniaturized Solid Phase Extraction and LC-MS/MS Detection of 3-Nitrotyrosine in Human Urine for Clinical Applications
Published on: July 14, 2017
Ultrasensitive strips for the quadruple detection of nitrofuran metabolite residues
Wei Wu1, Ning Sun2, Simin Zhu3
1College of Food Science and Engineering, Qingdao Agricultural University No. 700 Changcheng Road Qingdao 266179 China rice407@163.com.
Abstract:
In this biosensor system, metabolite residues were derived by using a previous B-CBA synthesis method to label a biotin moiety for enrichment by streptavidin coated magnetic beads. Antibodies specific for derivatives were conjugated with carboxyl-modified barcode DNAs which were used as templates for strand displacement amplification (SDA). The assay can detect trace levels of 7.20 ppt of SEM, 11.58 ppt of AHD, 7.24 ppt of AOZ and 2.31 ppt of AMOZ, respectively.
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