Predicting Outcomes in Trauma Patients With Cirrhosis Using Model for End-Stage Liver Disease Score: A Retrospective...

Area of Science:

• Trauma surgery
• Hepatology
• Critical care medicine

Background:

• Liver cirrhosis is a known risk factor for increased mortality in trauma patients.
• The specific impact of cirrhosis severity on trauma outcomes requires further stratification.

Purpose of the Study:

• To investigate the association between liver cirrhosis and mortality in trauma patients.
• To stratify the impact of cirrhosis on trauma mortality using the Model for End-stage Liver Disease (MELD) score.

Main Methods:

• Retrospective analysis of trauma center data from 2014-2018.
• Matched cohort study comparing cirrhosis patients (n=182) to controls (2:1 ratio) based on age, sex, and TRISS.
• Primary outcome: mortality; Secondary outcomes: length of stay, ICU days, ventilator days.

Main Results:

• Overall mortality was not significantly different between cirrhosis and control groups (7% vs 4%, p=0.38).
• No significant differences were observed in secondary outcomes.
• A 1.9-fold increased odds of mortality was associated with each increase in MELD score category (p=0.03).

Conclusions:

• The Model for End-stage Liver Disease (MELD) score can effectively estimate the mortality risk associated with cirrhosis in trauma patients.
• Cirrhosis severity, as indicated by MELD score, is a crucial factor in predicting outcomes for trauma victims.