Interobserver Variability in CT-based Morphologic Tumor Response Assessment of Colorectal Liver Metastases

Nina J Wesdorp¹, Ruby Kemna¹, Karen Bolhuis¹+30

• ¹From the Department of Surgery (N.J.W., R.K., G.K.) and Department of Radiology and Nuclear Medicine (J.H.T.M.v.W., I.M.G.C.N., F.S., I.O.A., S.S.K.S.P., M.R.W.E., J.S.), Cancer Center Amsterdam, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, the Netherlands; Department of Medical Oncology (K.B., C.J.A.P.) and Department of Surgery (S.v.D., T.M.v.G., R.J.S.), Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands; Department of Medical Imaging, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands (M.J.v.A., J.J.H.); Department of Hepatobiliary, Transplantation, and Endocrine Surgery, Antwerp University Hospital, Antwerp, Belgium (T.C.); Department of Surgery, Maastricht University Medical Center, Maastricht, the Netherlands (C.H.C.D.); Department of Surgery, Universitätsklinikum Aachen, Aachen, Germany (C.H.C.D.); Department of Surgery, Onze Lieve Vrouwe Gasthuis Hospital, Amsterdam, the Netherlands (M.F.G.); Department of Surgical Oncology and Gastrointestinal Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands (D.G., C.V.); Department of Hepatobiliary Surgery and Liver Transplantation, University Medical Center Groningen, Groningen, the Netherlands (K.P.d.J., J.M.K.); Department of Surgery, Medical Spectrum Twente, Enschede, the Netherlands (M.S.L.L.); Department of Interventional Radiology, St Antonius Hospital, Nieuwegein, the Netherlands (K.P.v.L.); Department of Surgery, Regional Academic Cancer Center Utrecht, University Medical Center Utrecht and St Antonius Hospital, Nieuwegein, the Netherlands (I.Q.M.); Department of Surgery, Isala Hospital, Zwolle, the Netherlands (G.A.P.); Department of Surgery, Amphia Hospital, Breda, the Netherlands (A.M.R.); Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands (T.M.R.); Department of Surgery, Radboud University Medical Center, Radboud University Nijmegen, Nijmegen, the Netherlands (J.H.W.d.W.); Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands (C.J.A.P.); and Department of Health, SAS Institute, Huizen, the Netherlands (J.H.).