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Overview of Systemic Arteries01:11

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The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
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Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
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Myocarditis I: Introduction01:21

Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Nephrotic Syndrome I : Introduction01:24

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Pericarditis I: Introduction01:22

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Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
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Endocarditis I: Introduction01:25

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Related Experiment Video

Updated: Sep 24, 2025

Supervised Machine Learning for Semi-Quantification of Extracellular DNA in Glomerulonephritis
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Systemic vasculitis: one year in review 2022.

Gaetano La Rocca1, Giulia Del Frate2, Paolo Delvino3

  • 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Italy.

Clinical and Experimental Rheumatology
|May 6, 2022
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Summary
This summary is machine-generated.

This review covers recent advancements in understanding systemic vasculitis, rare inflammatory disorders affecting blood vessels. It digests new findings on causes, symptoms, diagnosis, and treatments for small- and large-vessel vasculitis.

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Area of Science:

  • Rheumatology
  • Immunology
  • Internal Medicine

Background:

  • Systemic vasculitis encompasses rare, heterogeneous inflammatory disorders affecting any organ system.
  • These conditions carry a significant burden of mortality and comorbidity.
  • Annual reviews critically digest recent literature to inform clinical practice.

Purpose of the Study:

  • To provide a critical digest of the latest literature on systemic vasculitis.
  • To cover recent advancements in pathophysiology, clinical manifestations, diagnostic tools, and treatment options.
  • To focus on both small- and large-vessel vasculitis.

Main Methods:

  • Literature review of recent publications.
  • Critical analysis of current research findings.
  • Synthesis of information on vasculitis pathophysiology and clinical aspects.

Main Results:

  • Identification of emerging trends in vasculitis research.
  • Consolidation of updated knowledge on disease mechanisms.
  • Overview of evolving diagnostic and therapeutic strategies.

Conclusions:

  • The review synthesizes key developments in the field of systemic vasculitis.
  • It highlights the importance of ongoing research for improving patient outcomes.
  • Provides a current perspective on managing small- and large-vessel vasculitis.