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Characterization of pseudokinase ILK-mediated actin assembly

Julia Vaynberg1, Jun Qin1

  • 1Department of Cardiovascular & Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.

Methods in Enzymology
|May 7, 2022
PubMed
Summary

The integrin-linked kinase (ILK) complex (IPP) binds actin to form unique bundles, linking cell adhesion structures and the cytoskeleton. This process is crucial for cell spreading and migration.

Keywords:
Actin bundlingCell adhesionILKIntegrinPseudokinase

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