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Excess Pressure Inside a Drop and a Bubble01:13

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The shape of a small drop of liquid can be considered spherical, neglecting the effect of gravity. This drop can further be considered as two equal hemispherical drops put together due to surface tension. The forces acting on the spherical drop are due to the pressure of the liquid inside the drop, the pressure due to air outside the drop, and the force due to the surface tension acting on the two hemispherical drops.
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Microbubble Fabrication of Concave-porosity PDMS Beads
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Advances in antibubble formation and potential applications.

Rabia Zia1, Akmal Nazir2, Albert T Poortinga3

  • 1Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands.

Advances in Colloid and Interface Science
|May 8, 2022
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Summary

Antibubbles, liquid drops with air shells, offer potential for drug delivery but are short-lived. This review explores their generation, stability, and applications.

Keywords:
Air-liquid interfaceAntibubbleBubbleLiquid marblePickering emulsionStability

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Area of Science:

  • Physical Chemistry
  • Colloid Science
  • Materials Science

Background:

  • Antibubbles are unique structures with a liquid core and an air shell, featuring two air-liquid interfaces.
  • Their distinct architecture presents significant potential for applications like drug and therapeutic delivery.
  • However, their practical use is hindered by limited stability, often lasting only minutes to hours.

Purpose of the Study:

  • To provide a comprehensive overview of antibubble generation techniques.
  • To discuss the mechanisms governing antibubble formation, collapse, and stability.
  • To identify research gaps and suggest future research directions for antibubble applications.

Main Methods:

  • Review of conventional and novel antibubble generation methods.
  • Analysis of formation mechanisms, including surface entrapment, drop encapsulation, and emulsion evaporation.
  • Discussion of factors influencing antibubble stability and comparison with related structures (bubbles, liquid marbles).

Main Results:

  • Detailed examination of various methods for creating antibubbles.
  • Elucidation of the physical principles behind antibubble stability and degradation.
  • Identification of key challenges and opportunities for advancing antibubble technology.

Conclusions:

  • Antibubble generation involves diverse physical processes.
  • Stability remains a critical factor limiting widespread application.
  • Further research is needed to overcome stability limitations and realize the therapeutic potential of antibubbles.