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Molecular imaging nanoprobes for theranostic applications
Haozhe He1, Xindan Zhang2, Lihua Du3
1Nanomedicine Research Center, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China; Department of Pediatrics, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China.
Advanced Drug Delivery Reviews
|May 8, 2022
Summary
Molecular imaging nanoprobes offer non-invasive disease detection and treatment monitoring. This review summarizes recent advances in ultrasound, MRI, and CT nanoprobes, highlighting their applications and future directions.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Medical Imaging
Background:
- Molecular imaging enables in vivo detection of disease biomarkers for early diagnosis and treatment assessment.
- Nanosized imaging probes are crucial for molecular imaging, integrating chemistry, medicine, biology, and material science.
- Despite advancements, a comprehensive summary of recent nanoprobe progress is lacking.
Purpose of the Study:
- To review recent progress in three major types of molecular imaging nanoprobes: ultrasound (US), magnetic resonance imaging (MRI), and computed tomography (CT).
- To discuss the applications of these nanoprobes in detail.
- To provide an outlook on the future development of next-generation molecular imaging nanoprobes.
Main Methods:
- Literature review focusing on recent advancements in US, MRI, and CT nanoprobes.
- Categorization and discussion of nanoprobe types based on imaging modality.
- Analysis of reported applications and future trends.
Main Results:
- Detailed summary of recent progress in US, MRI, and CT nanoprobes.
- Exploration of diverse applications of molecular imaging nanoprobes.
- Identification of key areas for future research and development.
Conclusions:
- Nanosized probes are essential for advancing molecular imaging techniques.
- Continued innovation in nanoprobe design and application is critical for improving disease diagnosis and treatment.
- The field is poised for significant advancements in next-generation molecular imaging nanoprobes.
