Related Experiment Video
Updated: Sep 24, 2025

Author Spotlight: Exploring Plasticity of Sympathetic Neurons
Published on: July 5, 2024
Sympathetic Blocks for Visceral Pain
Kevin Vorenkamp1, Peter Yi2, Adam Kemp2
1Division of Pain Medicine, Duke Anesthesiology, Duke University, 2080 Duke University Road, Durham, NC 27708, USA.
Abstract:
For patients with chronic pain or cancer-related pain, the most common indication for sympathetic block is to control visceral pain arising from malignancies or other alterations of the abdominal and pelvic viscera. When it is recalcitrant to conservative care, or if the patient is intolerant to pharmacotherapy, consideration of sympathetic blocks or neurolytic procedures is considered. Potential advantages of a neurolytic procedure, compared with spinal and epidural anesthetic infusions, include cost savings and avoidance of hardware. Interventional therapies that target afferent visceral innervation via the sympathetic ganglia offer effective and durable analgesia and improve multiple metrics of quality of life.
More Related Videos
06:06In Vivo Calcium Imaging of Dorsal Root Ganglia Neurons' Response to Somatic and Visceral Stimuli
Published on: March 1, 2024
06:48Ethanol-Induced Cervical Sympathetic Ganglion Block Applications for Promoting Canine Inferior Alveolar Nerve Regeneration Using an Artificial Nerve
Published on: November 30, 2018
Related Concept Videos
Drugs Acting on Autonomic Ganglia: Blockers
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Sympathetic Pathways: Sympathetic Chain Ganglia
Sympathetic Division of the ANS
Originating in the thoracic and lumbar spinal cord segments, the preganglionic fibers of the sympathetic division exit the spinal cord through the white ramus communicans. They then enter the...
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Sympathetic Signaling
Sympathetic preganglionic fibers release the neurotransmitter acetylcholine (ACh) onto the ganglionic neurons in the...