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Evaluation of Left Diastolic Function in Dilated Cardiomyopathy According to the 2016 ASE/EACVI Recommendations

Quang Tuan Pham1, Thua Nguyen Tran2, Thanh Thuy Le-Thi1

  • 1Cardiology Department, Hue Central Hospital, Hue City, Vietnam.

International Journal of General Medicine
|May 9, 2022
PubMed

Insights

This study found that most dilated cardiomyopathy patients have severe diastolic dysfunction (grades II-III). Echocardiography is crucial for assessing this dysfunction and its relation to heart failure severity.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Heart Failure Research

Background:

  • Dilated cardiomyopathy (DCM) is a significant cause of heart failure.
  • Left ventricular diastolic dysfunction is a key pathophysiological feature in DCM.
  • Echocardiography is a primary tool for assessing cardiac function.

Purpose of the Study:

  • To evaluate left ventricular diastolic function in DCM patients using echocardiography.
  • To investigate the relationship between diastolic function and indicators like left ventricular dilatation, NYHA class, ejection fraction, and fractional shortening.

Main Methods:

  • A descriptive cross-sectional study was conducted.
  • Patients with primary dilated cardiomyopathy were recruited from Hue Central Hospital.
  • Echocardiography was used to assess left ventricular diastolic function and related parameters.

Main Results:

  • The majority of DCM patients exhibited severe diastolic dysfunction (Grade II: 44.6%, Grade III: 35.8%).
  • A moderate positive correlation was observed between left ventricular diastolic dysfunction and NYHA heart failure class (r=0.445, p<0.001).
  • Mean LVEF was 24.68±5.97% and mean LVFS was 12.91±4.55%.

Conclusions:

  • Routine echocardiographic evaluation of diastolic function is essential for understanding DCM pathogenesis and guiding patient management.
  • The 2016 ASE/EACVI recommendations offer a convenient approach to assessing diastolic function.
  • Severe diastolic dysfunction is prevalent in patients with dilated cardiomyopathy.
Abstract

Keywords:
dilated cardiomyopathyleft ventricular diastolic dysfunction

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