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A novel phenolic formulation for treating hepatic and peripheral insulin resistance by regulating GLUT4-mediated

Bean Bu Kang1,2, Been Huang Chiang1

  • 1Institute of Food Science and Technology, National Taiwan University, Taipei, Taiwan.

Journal of Traditional and Complementary Medicine
|May 9, 2022
PubMed

Keywords:
ACC, acetyl-CoA carboxylaseAbbreviations: 2DG, 2-deoxyglucoseBSA, bovine serum albuminBt2-cAMP, dibutyryl cAMPCB, cytochalasin BDAB, diaminobenzidineDMEM, Dulbecco's modified Eagle's mediumDMSO, dimethyl sulfoxideECL, enhanced chemiluminescenceEGCG, epigallocatechin-3-O-gallateEndosomeFBS, fetal bovine serumFER, ferulic acidGLUT4GLUT4, glucose transporter-4Glucose uptakeHepatic glucose productionIDV, indinavirIMCL, intramyocellular lipidISP, insulin signaling pathwayInsulin resistanceKHB, Krebs-Henseleit bufferMetabolic syndromeORO, Oil Red OPBS, phosphate-buffered salinePVDF, polyvinylidene difluoridePhenolic phytochemicalsRSV, resveratrolSDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresisT2DM, type 2 diabetes mellitusTf-HRP, Transferrin conjugated to horseradish peroxidaseType 2 diabetesα-MEM, α-minimal essential medium

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