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Large-scale Reconstructions and Independent, Unbiased Clustering Based on Morphological Metrics to Classify Neurons in Selective Populations
Published on: February 15, 2017
Modal clustering of matrix-variate data
Federico Ferraccioli1, Giovanna Menardi1
1Padua, Italy Dipartimento di Scienze Statistiche, Università degli Studi di Padova.
Abstract:
The nonparametric formulation of density-based clustering, known as modal clustering, draws a correspondence between groups and the attraction domains of the modes of the density function underlying the data. Its probabilistic foundation allows for a natural, yet not trivial, generalization of the approach to the matrix-valued setting, increasingly widespread, for example, in longitudinal and multivariate spatio-temporal studies. In this work we introduce nonparametric estimators of matrix-variate distributions based on kernel methods, and analyze their asymptotic properties. Additionally, we propose a generalization of the mean-shift procedure for the identification of the modes of the estimated density. Given the intrinsic high dimensionality of matrix-variate data, we discuss some locally adaptive solutions to handle the problem. We test the procedure via extensive simulations, also with respect to some competitors, and illustrate its performance through two high-dimensional real data applications.
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