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Updated: Sep 24, 2025

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
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Recent progress in development of 2,3-diaminomaleonitrile (DAMN) based chemosensors for sensing of ionic and reactive

Aruna1, Bhawna Rani1, Suman Swami1

  • 1Department of Chemistry, Manipal University Jaipur VPO-Dehmi-Kalan, Off Jaipur-Ajmer Express Way Jaipur Rajasthan India 303007 rahul.shrivastava@jaipur.manipal.edu arunava.agarwala@jaipur.manipal.edu.

RSC Advances
|May 9, 2022
PubMed

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Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
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