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Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Nawar Al Nasrallah1, Benjamin M Wiese1, Catherine R Sears1,2

  • 1Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.

Frontiers in Oncology
|May 9, 2022
PubMed
Summary

Xeroderma pigmentosum complementation group C (XPC) protein is crucial for DNA repair and preventing skin cancer. Emerging research highlights its broader role in non-dermatologic cancers, suggesting potential as a biomarker.

Keywords:
base excision repair (BER)biomarkerbladder cancerchemotherapylung cancernucleotide excision repair (NER)xeroderma pigmentosum (XP)

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