Related Experiment Video
Updated: Sep 24, 2025

07:38
Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
Published on: June 14, 2020
7.6K
Rectal Tonsil in a Patient With Positive Syphilis Serology
Daniel D Cain1, Kathleen Martin2, Bradley Gibson3
1Medical School, University of Pikeville, Kentucky College of Osteopathic Medicine, Pikeville, USA.
Cureus
|May 9, 2022
Summary
Rectal tonsils, a rare lymphoid mass in the rectum, can develop from antigen exposure. This case highlights their incidental discovery during a colonoscopy in a patient with iron deficiency anemia.
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Lymphoid tissue in the gastrointestinal tract can undergo reactive hyperplasia.
- Antigen exposure in the GI tract may trigger lymphoid tissue proliferation.
- Rectal tonsils represent a rare, localized proliferation of rectal lymphoid tissue.
Observation:
- A 46-year-old woman presented with iron deficiency anemia.
- Colonoscopy revealed an incidental finding of a rectal tonsil.
- The lymphoid mass was identified as a rectal tonsil.
Findings:
- Pathological analysis confirmed the rectal tonsil diagnosis.
- Further testing was conducted to evaluate the mass.
- Surgical removal of the rectal tonsil was performed.
Implications:
- This case expands the understanding of rectal tonsil presentation.
- Highlights the importance of thorough workup for incidental gastrointestinal findings.
- Contributes to the literature on the management of rare rectal lymphoid masses.
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