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Alkene hydroboration with pinacolborane catalysed by lithium diisobutyl-tert-butoxyaluminum hydride
Ashok Kumar Jaladi1, Won Kyu Shin1, Duk Keun An1
1Department of Chemistry, Institute for Molecular Science and Fusion Technology, Kangwon National University Chunchon 24341 Republic of Korea dkan@kangwon.ac.kr.
Abstract:
Here we developed a highly efficient alkene hydroboration protocol, showing that various alkyl boronates can be smoothly obtained in good yields by reacting alkenes with pinacolborane (HBpin) in the presence of 5 mol% lithium diisobutyl-tert-butoxyaluminum hydride. The coordination of aluminate ions with lithium cations allowed for effective hydride transfer during hydroboration, and the obtained boronate ester was further used for C-C coupling, trifluoroboronate salt formation, and oxidation to alcohol.
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