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Biomaterials for bone tissue engineering scaffolds: a review
Huawei Qu1, Hongya Fu1, Zhenyu Han1
1School of Mechatronics Engineering, Harbin Institute of Technology Harbin 150001 China hongyafu@hit.edu.cn.
RSC Advances
|May 9, 2022
Summary
This review explores biomaterials for bone tissue engineering scaffolds, covering their properties, applications, and the impact of additives like stem cells and signaling molecules for enhanced bone regeneration.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Orthopedic Engineering
Background:
- Bone tissue engineering is crucial for regenerating bone defects.
- Biomaterials are fundamental components of scaffolds used in bone regeneration.
- Understanding natural bone structure and properties informs scaffold design.
Purpose of the Study:
- To review literature on biomaterials for bone tissue engineering scaffolds.
- To detail the history, types, properties, and applications of these biomaterials.
- To discuss the influence of additives on scaffold performance.
Main Methods:
- Literature search strategy outlined.
- Review of natural bone characteristics.
- Analysis of biomaterial properties and applications in scaffold fabrication.
Main Results:
- Biomaterials are key to scaffold fabrication in bone tissue engineering.
- Various biomaterials exhibit diverse properties and applications.
- Additives significantly influence scaffold performance for bone regeneration.
Conclusions:
- Biomaterial selection is critical for successful bone tissue engineering.
- Further research into biomaterial-additive interactions can optimize scaffold design.
- This review provides a comprehensive overview of biomaterials in bone regeneration strategies.
