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Published on: January 26, 2024
Atypical Eclampsia in a Pregnant Woman Infected by COVID-19
Maha Ahmad Odeh1, Yousef S Abuzneid1, Omar Badareen2
1Al-Quds University Faculty of Medicine, Jerusalem, State of Palestine.
Insights
This case report details a pregnant woman with COVID-19 who experienced seizures, presenting an unusual manifestation of both the virus and eclampsia. The case highlights the complex neurological challenges COVID-19 can pose during pregnancy.
Area of Science:
- Neurology
- Infectious Diseases
- Obstetrics & Gynecology
Background:
- Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a pandemic with multi-organ effects.
- While COVID-19 in pregnancy is documented, severe neurological manifestations are less common.
- Eclampsia is a serious complication of pregnancy characterized by seizures.
Observation:
- A 34-week pregnant woman presented with tonic-clonic seizures.
- The patient was diagnosed with COVID-19.
- The presentation mimicked a novel manifestation of both COVID-19 and eclampsia.
Findings:
- This case highlights a rare neurological complication of COVID-19 in pregnancy.
- The patient's symptoms presented a diagnostic challenge, overlapping with eclampsia.
- The case underscores the need to consider diverse COVID-19 presentations in pregnant individuals.
Implications:
- This case expands the understanding of COVID-19's neurological impact on pregnant patients.
- It emphasizes the importance of considering COVID-19 in the differential diagnosis of seizures during pregnancy.
- Further research is needed to elucidate the mechanisms behind COVID-19-associated neurological complications in pregnancy.
Abstract:
The coronavirus disease 2019, also called (COVID-19), is an infectious disease which is caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first report was in December 2019, and on March 12, 2020, the World Health Organization (WHO) declared this disease a pandemic. COVID-19 targets many major organs causing life-threatening systemic complications. It can cause lung damage and respiratory failure in addition to systemic inflammation and immune dysregulation. Hypercoagulable state and numerous neurological abnormalities also have been reported due to this condition. Going through the literature review, we found some cases of pregnant women with novel coronavirus infection, being mostly mild illnesses, and most of these cases were focused on maternal-fetal transmission and neonatal outcomes. In this case report, we present the case of a COVID-19 positive woman who came to our emergency department at 34 weeks of gestation with tonic-clonic seizures. This case was a challenge for us because we faced a new an unknown manifestation of both COVID and eclampsia.
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