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Published on: March 6, 2018
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Metastatic prostate carcinoma presenting as a gluteal soft tissue mass
Jeff John1, Noma Mngqi2, Alessandro Pietro Aldera3
1Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London 5200, South Africa.
Therapeutic Advances in Urology
|May 9, 2022
Summary
Prostate adenocarcinoma metastasis to soft tissue is rare. This case highlights a painless gluteal mass, successfully treated with androgen deprivation therapy and chemotherapy, showing excellent response.
Area of Science:
- Oncology
- Urology
Background:
- Prostate adenocarcinoma commonly metastasizes to bone and lymph nodes.
- Soft tissue metastasis from prostate cancer is exceptionally uncommon.
Observation:
- A 56-year-old male presented with a two-year history of a painless right gluteal mass.
- MRI revealed a soft tissue mass and multifocal bone lesions suggestive of metastatic disease.
- Biopsy confirmed metastatic adenocarcinoma in the gluteal mass.
Findings:
- Elevated prostate-specific antigen (PSA) confirmed prostate as the primary source.
- Acinar adenocarcinoma of the prostate was diagnosed.
- The patient responded well to androgen deprivation therapy and chemotherapy, with resolution of the gluteal metastasis.
Implications:
- This case underscores the possibility of rare soft tissue metastases from prostate cancer.
- Effective treatment strategies can lead to significant clinical improvement and resolution of unusual metastatic sites.
- Highlights the importance of comprehensive workup for unexplained masses in prostate cancer patients.
