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Vaccinations01:51

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Optimization methods for large-scale vaccine supply chains: a rapid review.

Juliano Marçal Lopes1, Coralys Colon Morales2, Michelle Alvarado2

  • 1Gaesi, Departament of Electric Energy and Automation Engineering, Polytechnic School, University of São Paulo, São Paulo, SP Brazil.

Annals of Operations Research
|May 9, 2022
PubMed
Summary
This summary is machine-generated.

Optimization approaches can improve vaccine supply chain management, addressing challenges in resource allocation and distribution. However, few studies focus on inventory and logistics optimization, highlighting a critical research gap for pandemic preparedness.

Keywords:
LogisticsOptimizationRapid reviewSupply chainVaccination strategyVaccineVaccine allocation

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Area of Science:

  • Operations Research
  • Public Health
  • Supply Chain Management

Background:

  • Global vaccine revenues are substantial, yet effective large-scale vaccine distribution faces significant challenges worldwide.
  • Inefficient vaccine supply chain management can precipitate disease outbreaks and pandemics.
  • Optimization techniques offer potential solutions for improving vaccine logistics and resource allocation.

Purpose of the Study:

  • To review and analyze the application of optimization methods in vaccine supply chain and logistics.
  • To identify research trends, common optimization techniques, and areas lacking attention in the field.

Main Methods:

  • A rapid review of peer-reviewed journal articles published between 2009 and March 2020 was conducted.
  • Searches were performed across four scientific databases, yielding 25 relevant studies for analysis.
  • Data extracted included research objectives, supply chain stages, optimization methods, and consideration of uncertainties.

Main Results:

  • The majority of studies (64%) focused on vaccination strategy, with fewer addressing logistics and inventory management (36%).
  • Common optimization methods included control theory, linear programming, mathematical modeling, and mixed-integer programming (12% each).
  • Only 44% of studies incorporated uncertainties, and a notable lack of research was observed in vaccine inventory and logistics optimization.

Conclusions:

  • Optimization models have been applied to various aspects of vaccine supply chains, primarily vaccination strategies.
  • There is a significant need for increased research utilizing optimization for vaccine inventory management and logistics to enhance global health security.