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Related Concept Videos

Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

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Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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Peptide Identification Using Tandem Mass Spectrometry01:33

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Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
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Mass Spectrometry: Overview01:19

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Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass spectrometry is to generate ions from the analyte molecule and measure these ion abundances against their molecular mass.  One common type of ionization, known as electrospray ionization or EI, bombards the analyte molecules in the gas phase with high-energy electron beams. The electron beams displace an electron from the molecule and leave...
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Mass Spectrometers01:16

Mass Spectrometers

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This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
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Mass Spectrum: Interpretation01:24

Mass Spectrum: Interpretation

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An unknown compound can be established by identifying the molecular ion peak in the mass spectrum. The molecular ion peak is often weak or absent due to the predominance of fragmentation in high-energy electron beams. In such cases, a low-energy electron beam can be used to scan the spectrum to enhance the intensity of the molecular ion peak. Additionally, chemical ionization, field ionization, and desorption ionization spectra are used to obtain a relatively intense molecular ion peak.
To...
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High-Resolution Mass Spectrometry (HRMS)01:15

High-Resolution Mass Spectrometry (HRMS)

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The resolution of a mass spectrometer depends on the efficiency of separating ions with different ion masses. The mass of an atom is approximated to the sum of the masses of protons and neutrons inside, considering the masses of protons and neutrons as equal. However, the masses of the proton (1.6726 × 10−24 g) and neutron (1.6749 × 10−24 g) are not truly equal. There is a minor error in the expression of atomic masses relative to the simplest atom of hydrogen. For...
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Related Experiment Video

Updated: Sep 24, 2025

Species Determination and Quantitation in Mixtures Using MRM Mass Spectrometry of Peptides Applied to Meat Authentication
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Mass spectrometry in food authentication and origin traceability.

Xinjing Dou1, Liangxiao Zhang1,2,3,4, Ruinan Yang1

  • 1Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan, China.

Mass Spectrometry Reviews
|May 9, 2022
PubMed
Summary

Mass spectrometry (MS) is crucial for food authentication and origin traceability. This review highlights MS applications, new techniques like ambient ionization mass spectrometry (AIMS), and trends for ensuring food quality and detecting adulteration.

Keywords:
adulteration detectionanalytical techniquefingerprintfood authenticationmarkersmass spectrometryorigin traceability

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Area of Science:

  • Food Science
  • Analytical Chemistry
  • Spectroscopy

Background:

  • Growing consumer concerns about food quality and safety necessitate reliable methods for food authentication and origin traceability.
  • Mass spectrometry (MS) has emerged as a powerful analytical technique for addressing these challenges in the food industry.

Purpose of the Study:

  • To review the diverse applications of mass spectrometry (MS) in food authentication and origin traceability.
  • To discuss characteristic markers, advantages, disadvantages, and emerging trends in MS-based food analysis.
  • To provide a comprehensive guide for utilizing MS in food authentication and traceability.

Main Methods:

  • Analysis of main food components and chemical fingerprints/profiles using mass spectrometry.
  • Application of multivariate statistical analysis for fingerprinting and profiling methods.
  • Review of characteristic marker-based methods for adulteration detection.

Main Results:

  • Mass spectrometry techniques, particularly fingerprinting/profiling with statistical analysis, are effective for high-value food authentication.
  • Characteristic marker-based methods are suitable for detecting food adulteration.
  • Emerging techniques like proton transfer reaction mass spectrometry, ambient ionization mass spectrometry (AIMS), and ion mobility mass spectrometry offer rapid analysis for adulteration detection.

Conclusions:

  • Miniaturization of MS instruments enables portable, fast, and non-destructive food analysis.
  • Ambient ionization mass spectrometry (AIMS) is increasingly used for on-site food inspection and field analysis.
  • This review serves as a valuable reference for employing MS in food authentication and traceability.