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Updated: Sep 24, 2025
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Endovascular Thrombectomy Eligibility in the 0-24-Hour Time Window at a Large Academic Center in India
Deepti Vibha1, Shubham Misra1, Shashvat M Desai2,3
1Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Background:
The data regarding patients eligible for endovascular thrombectomy (EVT), especially in the developing world is lacking.
Objective:
To determine the proportion of patients with acute ischemic stroke (AIS) who are eligible for EVT in the 0-24-h time window.
Materials And Methods:
We performed a retrospective cohort study using prospectively collected AIS data between July 2017 and September 2019. Demographic, clinical, and management information were analyzed. EVT eligibility was explored using the following criteria: National Institutes of Health Stroke Scale (NIHSS) score ≥6, presence of anterior circulation large-vessel occlusion (ACLVO), Alberta stroke program early Computerized Tomography score (ASPECTS) ≥6, baseline modified Rankin Scale (mRS) score 0-2, and within 24 h of time last seen well (TLSW). EVT-eligible patients were further evaluated for in-hospital course and outcomes.
Results:
In the study period of 27 months, there were 221 patients with AIS who presented within 24 h. The mean age of the patients was 54.4 (16.0) years and 66.1% (146) were males. A majority (61.5% [136/221]) arrived within 6 h of TLSW. Of these, 81.6% (111/136) presented in the time window for thrombolysis (0-4.5 h). The patients with NIHSS ≥6 and ACLVO constituted 41.2% (91/221) of the patients. AIS eligible for EVT constituted 19.5% (43/221) of the patients.
Conclusion:
In our study, the proportion of AIS eligible for endovascular thrombectomy was comparable to the developed world. These data predict a large potential for the late-window EVT in India.
