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Adverse Cutaneous Drug Reactions in Children: A Retrospective Study in a Tertiary Hospital

Sofia Lopes1, Mariana Esteves2, Bonito Vitor3

  • 1Department of Dermatology and Venereology Centro Hospitalar e Universitário São João EPE, Porto, Portugal; sofialopes88@gmail.com.

Skinmed
|May 9, 2022
PubMed

Insights

Adverse drug reactions in children, especially skin reactions, are a significant health issue. This study characterized pediatric patients diagnosed with cutaneous adverse drug reactions (CADRs) at a tertiary hospital.

Area of Science:

  • Pediatric Dermatology
  • Pharmacovigilance
  • Clinical Pediatrics

Background:

  • Adverse drug reactions (ADRs) pose a significant health risk, with children being especially susceptible.
  • Cutaneous adverse drug reactions (CADRs) represent a substantial proportion, 35%, of all drug-related adverse effects observed in pediatric populations.
  • Understanding the characteristics of CADRs in children is crucial for improving patient safety and clinical management.

Purpose of the Study:

  • To characterize the pediatric population diagnosed with cutaneous adverse drug reactions (CADRs).
  • To analyze the demographic and clinical features of children experiencing CADRs in a tertiary hospital setting.
  • To provide insights into the prevalence and patterns of CADRs in pediatric patients.

Main Methods:

  • Retrospective study design.
  • Analysis of medical records of pediatric patients admitted to a tertiary hospital over a 6-year period.
  • Identification and characterization of patients with a confirmed diagnosis of cutaneous adverse drug reactions.

Main Results:

  • The study identified and characterized the pediatric population with CADRs.
  • Specific demographic and clinical data related to CADRs in children were compiled.
  • The findings highlight the importance of recognizing CADRs in pediatric care.

Conclusions:

  • Cutaneous adverse drug reactions are a notable concern in pediatric medicine.
  • Characterizing CADRs in children is essential for risk management and prevention strategies.
  • Further research may elucidate specific drug triggers and management protocols for pediatric CADRs.

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