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Estimating the EQ-5D-5L value set for the Philippines.

Red Thaddeus D Miguel1, Adovich S Rivera2, Kent Jason G Cheng3

  • 1Institute of Health Policy and Development Studies, National Institutes of Health, University of the Philippines Manila, Manila, Philippines.

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
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Summary

A new value set for the EQ-5D-5L was developed using health preferences from the Philippine population. This EQ-5D-5L value set is recommended for Quality-Adjusted Life Years (QALYs) calculations in health technology assessments.

Keywords:
Developing countriesEQ-5D-5LHybrid mathematical modelingQALYUtility weights

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Area of Science:

  • Health Economics
  • Psychometrics
  • Societal Preferences

Background:

  • The Philippines recommends Quality-Adjusted Life Years (QALYs) for health technology assessments (HTA).
  • A specific value set for the EQ-5D-5L instrument is needed for the Philippine population.
  • This study addresses the need for a localized EQ-5D-5L value set.

Purpose of the Study:

  • To develop a value set for the EQ-5D-5L instrument.
  • To capture the health preferences of the healthy general adult population in the Philippines.
  • To support the use of QALYs in Philippine health technology assessments.

Main Methods:

  • Recruited 1000 healthy adults from the Philippine general population using stratified sampling.
  • Elicited participant preferences using Composite Time Trade-Off (C-TTO) and Discrete Choice Experiment (DCE) tasks.
  • Estimated value sets using 8- and 20-parameter models, selecting the best fit based on monotonicity, model fit, and parsimony.

Main Results:

  • The final sample approximated the general population demographics.
  • None of the 20-parameter models met monotonicity criteria.
  • An 8-parameter homoscedastic TTO-only model demonstrated the best fit, with mobility and pain/discomfort significantly impacting utilities.

Conclusions:

  • An 8-parameter homoscedastic TTO-only model was selected to represent Philippine EQ-5D-5L health state preferences.
  • The developed value set is recommended for QALY calculations in the Philippines.
  • This will aid HTA-informed coverage decisions within the country.